Ayatollah Mohammad Saleh Komeily was born in a spiritual family. His father was Hojat al-Islam Hassan Komeily who was born in Mashhad. Hassan Komeily became a cleric and he was famous for his Friday eve Suplication of Kumayl, which made people name him Komeily. As a result of a Policy by Reza Shah (secular king of Iran) to uniform Iranian clergymen, he was forced to migrate to Iraq and resided in the Najaf and Samarra. He continued his religious studies in reputable theology schools of both cities. Finally, he returned to Mashhad due to Saddam (the dictator of Iraq) pressures on Iranian citizens in Iraq. He passed away in 1977 and buried in Khajeh Rabie shrine in Mashhad where a big crowd specially clergymen attended his funeral ceremony.